CP-609754 - CAS# 1190094-64-4 glabin EPZ-6438 displayed a 35-fold selectivity

Name: CP-609754 - CAS# 1190094-64-4 glabin EPZ-6438 displayed a 35-fold selectivity
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Description

EPZ-6438 displayed a 35-fold selectivity versus EZH1 and >4

CP-609754 - CAS# 1190094-64-4 glabin EPZ-6438 displayed a 35-fold selectivityCP 609754 (LNK 754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity. The IC50 for inhibiting farnesylation of recombinant human H Ras is 0. 57 ng mL and recombinant K Ras is 46 ng mL. Product information CAS Number: 1190094 64 4 Molecular Weight: 479. 96 Formula: C29H22ClN3O2 Chemical Name: 6 [(R) (4 chlorophenyl)(hydroxy)(1 methyl 1H imidazol 5 yl)methyl] 4 (3 ethynylphenyl) 1 methyl 1,2 dihydroquinolin 2

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